statpearls-mcp
StatPearls
Documentation
StatPearls MCP Server
A Model Context Protocol (MCP) server that fetches disease information from StatPearls, a trusted source of peer-reviewed medical content.
Give your AI system a relaible source of medical knowledge for its next conversation.
Features
- Searches for diseases and medical conditions on StatPearls
- Retrieve comprehensive, reliable medical information from StatPearls
- Convert HTML content to well-formatted Markdown to make it AI-friendly
- Integrates with AI models via the Model Context Protocol

If you don't already have a Model Context Protocol (MCP) client:
If you are a casual user, you can use Claude Desktop to get started using MCP servers. It is a free and open-source desktop application that allows you to run MCP servers locally and connect to them.
If you are a power user/developer, I recommend using VSCode with the RooCode extension which enables you to connect in MCP servers to your development environment for infinite possibilities!
Installation
Once you have an MCP-capable AI client, you can run this server locally.
The easiest way to get up and running is to download the appropriate executable/binary for your OS from the releases page. This will give you a self-contained executable that you can run without any additional setup.
Place this executable in a directory of your choice. Then simply add the following to your `mcp_settings.json` file:
For Windows:
{
"mcpServers": {
...
"statpearls": {
"command": "{path_to_executable_here}\\statpearls-mcp.exe"
},
...
}
}
#### For Mac/Linux:{
"mcpServers": {
...
"statpearls": {
"command": "{path_to_executable_here}/statpearls-mcp"
},
...
}
}
### Installing via Smithery
To install statpearls-mcp for Claude Desktop automatically via [Smithery](https://smithery.ai/server/@jpoles1/statpearls-mcp):npx -y @smithery/cli install @jpoles1/statpearls-mcp --client claude
### For Developers:
You can also run the server from source. This requires [Bun](https://bun.sh/) to be installed on your system.
1. Clone the repository
2. Install dependencies (`bun install`)
3. Compile the server (`bun run build`)
4. Now you can add the server to your `mcp_settings.json` file:{
"mcpServers": {
...
"statpearls": {
"command": "node",
"args": [
"{path_to_proj_here}/dist/index.js"
]
},
...
}
}
## Tool Definition
The server provides a single tool:
- **statpearls_disease_info**: Fetches comprehensive, reliable medical information about diseases from StatPearls.
### Input Schema{
"query": "diabetes",
"format_options": {
"includeToc": true,
"maxLength": 50000
}
}
- `query`: Disease or medical condition to search for (required)
- `format_options`: Optional formatting preferences
- `includeToc`: Whether to include a table of contents (default: true)
- `maxLength`: Maximum length of the returned content in characters (default: 50000)
### Example Output
The tool returns formatted Markdown content with:
- Title and source information
- Table of contents (optional)
- Structured sections including etiology, epidemiology, pathophysiology, clinical features, diagnosis, treatment, and prognosis (when available)
## Development
### Project Structurestatpearls-mcp/
├── src/ # Source code
│ ├── index.ts # Main entry point and server setup
│ ├── test-html-parser.ts # Test utility for HTML parser
│ ├── test-statpearls-parser.ts # Test utility for StatPearls parser
│ ├── testrun.ts # Test runner utility
│ ├── tools/ # Tool definitions and handlers
│ │ └── statpearls.ts # StatPearls tool definition and handler
│ ├── services/ # Core functionality services
│ │ ├── search.ts # Search functionality
│ │ ├── content.ts # Content retrieval and processing
│ │ └── markdown.ts # HTML to Markdown conversion
│ ├── types/ # Type definitions
│ │ ├── index.ts # Common type definitions
│ │ └── statpearls.ts # StatPearls-specific type definitions
│ └── utils/ # Utility functions
│ ├── html.ts # HTML parsing utilities
│ ├── error.ts # Error handling utilities
│ └── statpearls-parser.ts # StatPearls content parsing utilities
├── scripts/ # Build and utility scripts
│ ├── build.ts # Build script for creating Node.js compatible bundle
│ ├── compile.ts # Script for compiling executables
│ ├── release.ts # Script for handling releases
│ └── version.ts # Script for managing versioning
├── dist/ # Build output directory (not in repository)
├── package.json # Project configuration and dependencies
├── tsconfig.json # TypeScript configuration
├── bun.lock # Bun dependency lock file
├── README.md # Main project documentation
└── RELEASE-PROCESS.md # Documentation for release process
### Building and Releasing
#### Building
The build process creates a single JavaScript file that can run with vanilla Node.js:Production build
bun run build
or
bun run build:prod
Development build
bun run build:dev
This creates a bundled file at `dist/index.js` that includes all dependencies.
#### Compiling Executables
You can compile platform-specific executables using Bun's compilation feature:Compile for all platforms
bun run compile:all
Compile for specific platforms
bun run compile:linux
bun run compile:windows
bun run compile:mac
This creates executable files in the `dist` directory:
- `statpearls-mcp` (default executable)
- `statpearls-mcp-linux-x64` (Linux)
- `statpearls-mcp-windows-x64.exe` (Windows)
- `statpearls-mcp-darwin-x64` (macOS)
#### Releasing
The release process handles versioning, building, compiling, and Git operations:Release a patch version (bug fixes)
bun run release:patch
Release a minor version (new features, backward compatible)
bun run release:minor
Release a major version (breaking changes)
bun run release:major
This process:
1. Updates the version in package.json
2. Builds the distribution file
3. Compiles executables for all platforms
4. Creates a Git commit with the version number
5. Creates a Git tag for the version
6. Pushes the commit and tag to GitHub
#### Versioning
The project follows semantic versioning. You can check the current version with:bun run version
## License
This project is licensed under the MIT License - see the LICENSE file for details.Frequently asked questions
What is statpearls-mcp?
statpearls-mcp is StatPearls
How do I install statpearls-mcp?
Open the GitHub repository and follow its README. Most MCP servers are added to your client's MCP config, then called by your agent.
Is statpearls-mcp open source?
Yes — it is hosted on GitHub at https://github.com/jpoles1/statpearls-mcp and has 1 stars.
Related MCP tools
Model Context Protocol Servers
The Open-Source Multimodal AI Agent Stack: Connecting Cutting-Edge AI Models and Agent Infra
A MCP for Claude Desktop / Claude Code / Windsurf / Cursor to build n8n workflows for you
MCP server to provide Figma layout information to AI coding agents like Cursor
The world's best AI personal assistant for email. Open source app to help you reach inbox zero fast.
Instant is the best backend for AI-coded apps. You get auth, permissions, storage, presence, and streams — everything you need to ship apps your users will love.
Run your own MCP server? See who uses it and what to fix.
Measure it with TrackMCP